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Step-by-step, together with your patients

Ionis Every Step™ is dedicated to helping your patients, offering a wide range of support and resources to meet your patient’s needs at each step of their treatment journey.

If your patient is new to DAWNZERA, they may be eligible to receive a one-time, one-dose supply of DAWNZERA at no cost to see if DAWNZERA is right for them. Fill out the Free Trial Prescription on the enrollment form or through DAWNZERA Direct to enroll your patient. For eligibility, see terms and conditions at DAWNZERA.com/FreeTrialProgam.*

*May not be billed back to the third-party payer or resold. Participating in the program does not impose an obligation to purchase in the future. Terms and conditions apply. Programs subject to change or discontinue without notice, including in specific states.

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Patient Education Manager†

Your patient is connected with a dedicated Patient Education Manager from the start, so you can feel confident that they’re supported at every step. The Patient Education Manager is your patient’s primary Ionis Every Step partner who is ready to:

  • Explain the process for getting DAWNZERA to your patient

  • Teach your patient how to inject DAWNZERA. Training is available in person or virtually, based on their preference

  • Keep your office updated throughout treatment

  • Reach out to your patient at every step to ensure they’re receiving the support they need

  • Answer your patient’s questions and provide educational resources about DAWNZERA or hereditary angioedema (HAE)

  • Connect your patient to additional Ionis Every Step team members for support

  • Support your patient based on your prescribed treatment plan

†Patient Education Managers do not provide clinical recommendations and will refer patients back to their health care providers as necessary.

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Insurance navigation‡

The Ionis Every Step Case Manager helps navigate your patient’s access to DAWNZERA by:

  • Completing a benefit verification

  • Identifying plan-specific requirements

  • Providing prior authorization, appeal, and reauthorization support

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Affordability programs§

Ionis Every Step is committed to helping your patient access their Ionis medication. With affordability programs for all insurance types, your patient can find a solution that helps them stay on track with DAWNZERA.

  • Quick Start||

  • Ionis Every Step may help get your patient started on therapy quickly with a quick-start shipment if insurance coverage is delayed.

  • Copay Assistance#

  • With commercial insurance coverage, an eligible patient may pay as little as $0 out-of-pocket for their DAWNZERA prescription.

If your patient’s insurance plan does not provide adequate coverage for DAWNZERA, our team will assess their eligibility for our affordability programs and provide the necessary information. Call 1-844-444-4305 for more information.

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DAWNZERA Direct online companion

DAWNZERA Direct is an online companion that allows you to stay connected to your patient’s treatment journey with DAWNZERA by:

  • Enabling you to prescribe DAWNZERA

  • Requesting a meeting with your Account Specialist

  • Discovering educational resources for HAE and the access process

  • Viewing your patient’s reported injection schedule, upcoming appointments, refill status, and plans to continue medication

Connect with your Account Specialist to gain access to DAWNZERA Direct.

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Ongoing support

Ionis Every Step offers resources to help your patients follow your prescribed treatment plan.

DAWNZERA AuthASSIST

  • Ionis Every Step is committed to helping your patient take their next steps with DAWNZERA. That’s why we offer comprehensive support to help you prepare for and navigate the reauthorization process

Resource Navigators

  • Support doesn't stop with the Patient Education Manager. Our Resource Navigator is your patient’s guide for local social and emotional support

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Insurance approval is not guaranteed. Ionis Every Step™ offers affordability programs for people prescribed DAWNZERA.

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Programs subject to change or discontinue without notice, including in specific states.

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Terms and conditions apply. Program subject to change or discontinue without notice, including in specific states.

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Eligibility restrictions: This program is not available to individuals who use any state or federal government-funded healthcare program to cover a portion of medication costs, such as Medicare, Medicaid, TRICARE, Department of Defense, or Veterans Administration, or any other state or federal government-funded healthcare program.

FAQ

Frequently asked questions about Ionis Every Step™

Once your patient signs up for Ionis Every Step, they will receive a Welcome Kit and a call from their dedicated Patient Education Manager, who will welcome them to the program and schedule administration training.

Your Ionis Account Specialist will inform you about your behind-the-scenes companion—the Ionis Every Step Case Manager! They help you verify benefits, identify plan-specific requirements, and provide prior authorization, appeal, and reauthorization support to get your patient access to their medication faster.*

*Insurance approval is not guaranteed. Ionis Every Step™ offers affordability programs for people prescribed DAWNZERA.

For patients without insurance, Ionis Every Step can help them understand what financial assistance options may be available to help them access DAWNZERA. Encourage them to call 1-844-444-4305, Monday to Friday, 8 AM to 8 PM ET, to check their eligibility for financial assistance.

If your patient didn’t sign the Patient Authorization and Consent section of the form in your office, they can sign up with one of the following ways:
 

1. Complete online here

2. Call Ionis Every Step at 1-844-444-4305, Monday to Friday, 8 AM to 8 PM ET

IMPORTANT SAFETY INFORMATION & INDICATION

CONTRAINDICATIONS

DAWNZERA is contraindicated in patients with a history of serious hypersensitivity reactions, including anaphylaxis, to donidalorsen or any of the excipients in DAWNZERA.

WARNINGS AND PRECAUTIONS

Hypersensitivity Reactions

Hypersensitivity reactions, including anaphylaxis, have been reported in patients treated with DAWNZERA. If signs and symptoms of serious hypersensitivity reactions occur, discontinue DAWNZERA and institute appropriate therapy.

ADVERSE REACTIONS

Most common adverse reactions (incidence ≥ 5%) are injection site reactions, upper respiratory tract infection, urinary tract infection, and abdominal discomfort.

INDICATION

DAWNZERA (donidalorsen) is indicated for prophylaxis to prevent attacks of hereditary angioedema (HAE) in adult and pediatric patients 12 years of age and older.

Please see full Prescribing Information for DAWNZERA.